#1 Gwyneth Paltrow Gwenyth Paltrow is so enthusiastic about the transformative power of supplements that she started her own line. The GOOP Cleanse is pricey. But who wouldn't be willing to invest a little for Gwenyth's good looks? #2 Jamie Lee Curtis Jamie Lee Curtis was one of the first celebrities to speak out in support of probiotics. The actress has been supplementing with healthy bacteria for years. They keep your colon healthy and maximize nutrient absorption even when you're on a diet. #3 Matthew McConaughey Matthew McConaughey's trainer got him ready for his role in "Magic Mike" with supplements. A Co-Q10 supplement paired with multi-vitamins and minerals helped him lose weight and build muscle in time for shooting. #4\u00a0Kirstie Alley Kirstie Alley is under fire for her use of supplements. The actress says that her calcium and fiber-based supplements helped her shed 100 pounds. However, critics say that her supplements are ineffective. Whatever the case, she still looks great. #6 Alicia Silverstone Alicia Silverstone, actress and vegan advocate, supplements with vitamin D3. Vitamin D deficiency has been linked to obesity in women and men.